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CD38 Mouse anti-Human, Clone: HIT2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119316

Catalog No. 01-676-072


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Description

Description

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.

A suggested positive control for this product is RAJI human cells.
Specifications

Specifications

CD38
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
P28907
T10, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, CD38 antigen p45, NAD+ nucleosidase, cADPr hydrolase 1, cyclic ADP-ribose hydrolase 1
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
952
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
HIT2
Unconjugated
CD38
Liquid
CD38
Fetal human thymocytes.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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