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MilliporeSigma™ anti-CD3e PE-Cy7, Clone: 145-2C11,

Armenian Hamster Monoclonal Antibody

Manufacturer:  MilliporeSigma™ MABF1581

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Catalog No. MABF1581MI


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Description

Description

Specifically detects CD3e Clone: 145-2C11 in Mouse samples, and it is validated for Flow Cytometry

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The 145-2C11 antibody is a widely used phenotypic marker for mouse T cells. In addition, binding of 145-2C11 antibody to CD3e can induce cell activation.
Specifications

Specifications

CD3e
145-2C11
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Purified
Armenian Hamster
IgG
25μg
Inflammation, Immunology
Primary
Murine
Flow Cytometry
PE-Cyanine7
P22646
Cd3e
Proprietary immunogen
Purified by size-exclusion chromatography
RUO
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Monoclonal
SDS
Documents
Product Certifications
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