CD4/CD25, FITC, PE, Clone: 7E14, ITYV, Antibody Cocktail, Invitrogen™
Manufacturer: Invitrogen MA112116
The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells. To date, a total of 151 CD clusters and subclusters have been identified.This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD25 (clone ITYV, isotype IgG1).
|human peripheral blood T lymphocytes and PHA-activated human T-lymphocytes|
|7E14, ITYV, ITYV|
|PBS with 0.2% carrier protein and 0.08% sodium azide|
|CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, IL-2R alpha, IL2 RA antibody, Il2ra antibody, Interleukin 2 receptor alpha chain antibody, TAC antigen antibody, IL-2R alpha chain|
|4° C, do not freeze, do not freeze|
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