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CD4/CD26 Mouse anti-Human, FITC, PE, Invitrogen™

Antibody Cocktail

Manufacturer:  Invitrogen MA112119

Catalog No. 01-670-838


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Description

Description

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD26 (clone EUG-6, isotype IgG2a).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein]. 1 - 3 is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti CD3-induced IL - 2 production.
Specifications

Specifications

CD4/CD26
Cocktail
FITC, PE
DPP4
Liquid
CD4, DPP4
human peripheral blood T lymphocytes
Protein A/G
RUO
Antibody
1803, 920
Flow Cytometry
7E14
PBS with 0.2% carrier protein and 0.08% sodium azide
P01730, P27487
CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, DPP4, ADABP, ADCP2, CD26, DPP-IV, TP103, ADCP-2, DPP IV, T-cell activation antigen CD26, adenosine deaminase complexing protein 2, dipeptidyl peptidase 4, dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidylpeptidase IV CD26, adenosine deaminase complexing protein 2
Mouse
IgG1/IgG2a
50 Tests
4° C, do not freeze
Primary
Human
Documents
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