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CD4/CD27 Mouse anti-Human, FITC, PE, Invitrogen™

Antibody Cocktail

Manufacturer:  Invitrogen MA112121

Catalog No. 01-670-840


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Description

Description

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD27 (clone DEN-3, isotype IgG1).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD27 (50 kDa) is a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 and CD30 are also members of the TNF receptor superfamily. The TNF superfamily members are known for the regulation of cell proliferation and death. In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predomitly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals. CD27 is a membranebound receptor, but a soluble form of CD27 is also produced.
Specifications

Specifications

CD4/CD27
Cocktail
FITC, PE
CD27
Liquid
CD27, CD4
human peripheral blood T lymphocytes
Protein A/G
RUO
Antibody
920, 939
Flow Cytometry
7E14
PBS with 0.2% carrier protein and 0.08% sodium azide
P01730, P26842
CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, TNFRSF7, CD27 antigen, CD27L receptor, T cell activation antigen CD27, T cell activation antigen S152, T-cell activation antigen CD27, tumor necrosis factor receptor superfamily member 7
Mouse
IgG1
50 Tests
4° C, do not freeze
Primary
Human
Documents
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