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CD4/CD28 Mouse anti-Human, FITC, PE, Invitrogen™

Antibody Cocktail

Manufacturer:  Invitrogen MA112122

Catalog No. 01-670-841


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Description

Description

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD28 (clone B-23, isotype IgG1).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells.
Specifications

Specifications

CD4/CD28
Cocktail
FITC, PE
CD28
Liquid
CD28, CD4
human peripheral blood T lymphocytes and HPB-ALL T-cell line
Protein A/G
RUO
Antibody
920, 940
Flow Cytometry
7E14, B-23
PBS with 0.2% carrier protein and 0.08% sodium azide
P01730, P10747
CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, MGC138290, Tp44, CD28 antigen, T-cell-specific surface glycoprotein CD28
Mouse
IgG1
100 Tests
4° C, do not freeze
Primary
Human
Documents
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