CD4/CD45RA, FITC, PE, Clone: 7E14, BHKG-2, Antibody Cocktail, Invitrogen
Manufacturer: Invitrogen MA112217
The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD45 Leukocyte Common Antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals.This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD45RA (clone BHKG-2, isotype IgG1).
|human peripheral blood T lymphocytes and peripheral blood monocytes from a rheumatoid arthritis patient|
|PBS with 0.2% carrier protein and 0.08% sodium azide|
|CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, protein tyrosine phosphatase, receptor type, c polypeptide, receptor-type tyrosine-protein phosphatase C|
|4° C, do not freeze|
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