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CD41 Rat anti-Mouse, Brilliant Violet 605, Clone: MWReg30, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 563317

Catalog No. BDB563317

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The MWReg30 antibody reacts with glycoprotein (gp) IIb, also called integrin αIIb chain (CD41), that associates with integrin β3 chain (gpIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.

For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment. Fluorescent dye interactions may cause staining artifacts which may affect data interpretation. The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794).

Specifications

Specifications

CD41
MWReg30
Brilliant Violet 605
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Rat
IgG1, κ
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
Integrin α IIb chain
Affinity Purified
Mouse Platelets
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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