CD44 Mouse anti-Human, Brilliant Violet 786, Clone: G44-26, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564942
The G44-26 monoclonal antibody specifically binds to the 80-95 kDa, glycosylated type I transmembrane protein, also known as phagocytic glycoprotein-1 (Pgp-1). CD44 is the receptor for hyaluronic acid. CD44 is expressed on leucocytes, erythrocytes, epithelial cells and weakly on platelets. CD44 is also called extracellular matrix receptor type III and has functional roles in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation. This antibody is suitable for staining formalin-fixed, paraffin-embedded tissue sections using citrate buffer pretreatment. This antibody recognizes the epitope 1 of CD44 antigen according to the HLDA workshop studies.
The antibody was conjugated to BD Horizon BV786 which is part of the BD Horizon Brilliant Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy7-like dyes (eg, 780/60-nm filter).
|Phagocytic glycoprotein 1; Pgp-1; H-CAM; Hermes; ECMR III; HUTCH-1|
|Brilliant Violet 786|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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