MilliporeSigma™ anti-CD44 FITC, Clone: IM7,

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
MABF1556MI	MilliporeSigma™ MABF1556	25 μg
MABF1557MI	MilliporeSigma™ MABF1557	100 μg
MABF1558MI	MilliporeSigma™ MABF1558	500 μg

Description

Specifically detects CD44 Clone: IM7 in Human, Mouse samples, and it is validated for Flow Cytometry

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or 'standard' form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

Specifications

• Antigen: CD44
• Applications: Flow Cytometry
• Conjugate: FITC
• Host Species: Rat
• Research Discipline: Inflammation, Immunology
• Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
• Gene Symbols: Cd44, Ly-24
• Isotype: IgG2b κ
• Purification Method: Purified by size-exclusion chromatography

• Clone: IM7
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Mouse
• Gene Accession No.: P15379
• Immunogen: Proprietary immunogen
• Primary or Secondary: Primary
• Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze

For Research Use Only