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CD14/CD45, FITC, PE, Clone: BHPT-1, FWKW, Antibody Cocktail, Invitrogen™

Antibody Cocktail

Manufacturer:  Invitrogen MA112220

Catalog No. 01-670-928

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS)-dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram-negative shock. CD45 Leukocyte Common Antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals.

This antibody is a monoclonal mixture of FITC-conjugated CD45 (clone BHPT-1, isotype IgG1) and PE-conjugated CD14 (clone FWKW, isotype IgG2b).
Specifications

Specifications

CD14/CD45
Cocktail
FITC, PE
PTPRC
Liquid
CD14, PTPRC
human peripheral blood monocytes from a rheumatoid arthritis patient
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
BHPT-1, FWKW, FWKW
PBS with 0.2% carrier protein and 0.08% sodium azide
P08571, P08575
monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein, PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, protein tyrosine phosphatase, receptor type, c polypeptide, receptor-type tyrosine-protein phosphatase C
Murine
IgG1/IgG2b
50 Tests
4° C, do not freeze, do not freeze
Primary
5788, 929
Documents
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