CD46 Mouse anti-Human, APC, Clone: E4.3, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564253
The E4.3 monoclonal antibody specifically binds to CD46. CD46 is also known as membrane cofactor protein (MCP). CD46 is a type I membrane glycoprotein composed of two non-disulfide linked α (66 kDa) and β (56 kDa) chains expressed on lymphocytes, monocytes and granulocytes. It is not expressed on erythrocytes or platelets. There are four isoforms of the dimer which function as complement regulatory factors. CD46 promotes the enzymatic degradation of activated C3b and/or C4b deposited on host cells. It also serves as the measles virus receptor.
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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