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CD46 Mouse anti-Bovine, Human, Clone: MEM-258, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119018

Catalog No. 01-674-991


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Description

Description

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

Western blot should be performed under non-reducing conditions.
Specifications

Specifications

CD46
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
Q6VE48, P15529
AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
280851, 4179
Flow Cytometry, Immunoprecipitation, Western Blot
MEM-258
Unconjugated
CD46
Liquid
CD46
T cell line HPB-ALL.
Protein A
RUO
Antibody
Monoclonal
Bovine, Human
Documents
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