CD49b Mouse anti-Human, Alexa Fluor 647, Clone: AK-7, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564314
The AK-7 monoclonal antibody specifically binds to CD49b. CD49b is also known as integrin α2 chain, VLA-α2, and GP1a. CD49b is a type I transmembrane glycoprotein and be longs to the integrin family of extracellular matrix and cell-cell adhesion receptors. CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes. CD49b noncovalently associates with CD29 to form the VLA-2 complex (integrin α 2/ β 1). The VLA-2 complex serves as a receptor for collagen and laminin. It can regulate responses mediated by proinflammatory effector cells.
|Integrin α2 chain; VLA-α2: GP1a|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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