CD5 Mouse anti-Human, Clone: CRIS1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119438
This antibody can be used as a detection antibody in a Sandwich ELISA with capture antibody MA1-19076.CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.
|PBS with 15mM sodium azide; pH 7.4|
|CD5 antigen p56-62, T-cell surface glycoprotein CD5, lymphocyte antigen T1/Leu-1|
|4° C, do not freeze|
|ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot|
|Stimulated human leukocytes.|
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