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CD50 Mouse anti-Human, Brilliant Violet 746, Clone: TU41 (also known as TÜ41), BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564212

Catalog No. BDB564212


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Description

Description

The TU41 monoclonal antibody specifically binds to the intracellular adhesion molecule-3 (ICAM-3) which is also known as CD50. ICAM-3 is a 110-120 kDa type I membrane glycoprotein expressed on all leukocytes (platelets and erythrocytes are ICAM-3-negative). ICAM-3 is also expressed on epidermal Langerhans cells and endothelial cells. It predominantly interacts with LFA-1 (CD11a/CD18) without requiring activation as the initial dendritic cell-T lymphocyte interaction. ICAM-3 is an important LFA-1 ligand that functions in the initiation of the immune/inflammatory response and also plays a role in chemotaxis.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Specifications

Specifications

CD50
TU41 (also known as TÜ41)
ICAM-3; ICAM3; Intercellular adhesion molecule 3
Affinity Purified
IgG2b, κ
RUO
Primary
Human
Flow Cytometry
Brilliant Violet 746
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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