ICAM-1 Mouse anti-Human, Clone: 1H4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119028
For IHC (P), prolonged fixation in buffered formalin can destroy the epitope. High temperature antigen unmasking technique is required.CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
|PBS with no preservative; pH 7.4|
|BB2, P3.58, ICAM-1, cell surface glycoprotein P3.58, intercellular adhesion molecule 1, human rhinovirus receptor, major group rhinovirus receptor|
|4° C, do not freeze|
|Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|Raji cells and spleen cells fused with NS1 cells.|
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