CD59 Mouse anti-Human, Biotin, Clone: MEM-43, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119504
CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
|PBS with 15mM sodium azide; pH 7.4|
|CD59, CD59 molecule complement regulatory protein, 1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20|
|4° C, do not freeze|
|Thymocytes and T lymphocytes.|
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