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Transferrin Receptor Mouse anti-Human, Clone: MEM-75, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119137

Catalog No. 01-675-909


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Description

Description

CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
Specifications

Specifications

Transferrin Receptor
Monoclonal
1 mg/mL
TBS with 15mM sodium azide; pH 8
P02786
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
7037
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
MEM-75
Unconjugated
TFRC
Liquid
TFRC
Pre-B cell line NALM-6.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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