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CD8/CD28 Mouse anti-Human, FITC, PE, Invitrogen™

Antibody Cocktail

Manufacturer:  Invitrogen MA112167

Catalog No. 01-670-886



Description

Description

This antibody is a monoclonal mixture of FITC-conjugated CD8 (clone 17D8, isotype IgG1) and PE-conjugated CD28 (clone B-23, isotype IgG1).

CD8 molecule is composed of two chains termed alpha and beta. CD8 is found on a T cell subset of normal cytotoxic / suppressor cells which make up approximately 20 to 35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15 to 30% of bone marrow cells. Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells.
Specifications

Specifications

CD8/CD28
Cocktail
FITC, PE
CD28
Liquid
CD28, CD8A, CD8B
human peripheral blood T lymphocytes and HPB-ALL T-cell line
Protein A/G
RUO
Antibody
925, 926, 940
Flow Cytometry
17D8
PBS with 0.2% carrier protein and 0.08% sodium azide
P01732, P10747, P10966
CD8, Leu-2, MAL, p32, CD8a, CD8b, CD8alpha, CD8beta, MGC138290, Tp44, CD28 antigen, T-cell-specific surface glycoprotein CD28
Mouse
IgG1
50 Tests
4° C, do not freeze
Primary
Human
Documents
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