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anti-CD8, Clone: SFCI21Thy2D3 (T8), Beckman Coulter™

$449.82 - $944.52

Specifications

Antigen CD8
Format Purified
Host Species Murine
Isotype IgG1
Monoclonal or Polyclonal Monoclonal
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
CO6602385
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Coulter Corporation
6602385
100 Tests
Each for $757.86
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CO6603861
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Coulter Corporation
6603861
50 Tests
Each for $449.82
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CO6607011
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Coulter Corporation
6607011
50 Tests
Each for $944.52
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Description

Description

The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8 alpha homodimer or as a CD8 alpha/beta heterodimer. CD8 beta is required for surface expression of CD8 alpha. The molecular weight of each monomer alpha or beta is approximatively 32-34 kDa. CD8 binds to a non polymorphic domain (alpha 3 domain) of the MHC Class I molecules. The CD8 molecule is found on a T cell subset of human peripheral blood lymphocytes. A subset of NK cells expresses the CD8 antigen but with low to medium density of expression. CD8 alpha homodimer is expressed by NK cells on gamma/delta+ T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a co-receptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes.

Host Species: Mouse
Clone: SFCI21Thy2D3 (T8)
Isotype: IgG1
Cross Reactivity: Human

Flow Cytometry, Immunoprecipitation

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Specifications

CD8
Murine
Monoclonal
Purified
IgG1
Primary
SDS
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