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MilliporeSigma™ anti-CD80 APC, Clone: 16-10A1,

Armenian Hamster Monoclonal Antibody

$157.10 - $343.00

Specifications

Antigen CD80
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Format Purified
Formulation Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MABF1554MI
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MilliporeSigma™
MABF1554
25μg
Each for $157.10
Add to cart
 
MABF1555MI
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MilliporeSigma™
MABF1555
100μg
Each for $343.00
Add to cart
 
Description

Description

Specifically detects CD80 Clone: 16-10A1 in Mouse samples, and it is validated for Flow Cytometry

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
Specifications

Specifications

CD80
Monoclonal
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Flow Cytometry
IgG
Q00609
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Inflammation, Immunology
Primary
Purified
16-10A1
Armenian Hamster
Proprietary immunogen
Cd80, B7
RUO
Purified by size-exclusion chromatography
SDS
Product Certifications

For Research Use Only

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