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CD80 Mouse anti-Human, Clone: MEM-233, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119215

Catalog No. 01-675-979


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Description

Description

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

Specifications

Specifications

CD80
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
P33681
B7-1, B7.1, Cd28l, Ly-53, Ly53, MIC17, TS/A-1, LAB7, B7.1, CD28LG, CD28LG1
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
941
Flow Cytometry, Immunoprecipitation
MEM-233
Unconjugated
CD80
Liquid
CD80
Extracellular domain of human CD80 fused to human IgG1(Fc).
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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