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CD86 Mouse anti-Human, FITC, Clone: 2331 (FUN-1), BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 557343
Description
2331 (FUN-1) recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86) recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. 2331 (FUN-1) blocks costimulation activity of CD86 in functional studies. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.Specifications
CD86 | |
Monoclonal | |
FITC | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human HBL-1 Cell Line | |
50 Tests | |
Immunology | |
Baboon, Cynomolgus, Rhesus Monkey | |
IgG1 κ |
Flow Cytometry | |
2331 (FUN-1) | |
B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72 | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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