CD86 Mouse anti-Human, V450, Clone: 2331 (FUN-1), BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB560359	BD Biosciences 560359	30 Tests
BDB560357	BD Biosciences 560357	120 Tests

Description

2331 (FUN-1) recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Mfr. No. 555663) recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. 2331 (FUN-1) blocks costimulation activity of CD86 in functional studies. The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

Host Species: Mouse
Clone: 2331(FUN-1)
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD86
• Applications: Flow Cytometry
• Conjugate: Violet Fluor 450 (V450)
• Regulatory Status: RUO
• Target Species: Human
• Immunogen: Human HBL-1 Cell Line
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: 2331 (FUN-1)
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Immunology
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

For Research Use Only.