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CD97 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528350

Catalog No. PIPA528350


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Description

Description

PA5-28351 targets RAD51B in WB applications and shows reactivity with Human samples. The PA5-28351 immunogen is recombit fragment corresponding to a region within amino acids 1 and 384 of Human RAD51B.

This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found.
Specifications

Specifications

CD97
Polyclonal
Unconjugated
ADGRE5
Liquid
ADGRE5
Recombit fragment corresponding to a region within amino acids 320 and 751 of Human CD97
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.53 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
P48960
CD97, CD97 molecule, Leukocyte antigen CD97, TM7LN1, CD97 antigen
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
976
Documents
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