Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD98 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA185012

Catalog No. PIPA185012


Add to cart

Description

Description

Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for immunohistochemical applications is placenta. In Western blot, this antibody detects a band at ~50-55kDa in human liver cell lysate. Rabbit anti Human CD98 light chain antibody detects an epitope within the N-terminal (NT) region of the CD98 light chain (CD98LC), also known as the 4F2 light chain, or LAT-1.

CD98 light chain (CD98LC), also known as the 4F2 light chain or LAT-1, is a 40kDa multi-pass membrane protein which forms a heterodimer with the CD98 heavy chain to allow transport of large branched chain, neutral amino acids into the cell. This transport system leads to the uptake of seven amino acids, including isoleucine, phenylalanine, and methionine. The expression levels of CD98LC are upregulated in a wide spectrum of primary human cancers. Changes in amino acid transporter expression are thought to be an early change in oncogenesis, as they impart growth and survival advantages.
Specifications

Specifications

CD98
Polyclonal
Unconjugated
SLC3A2
Liquid
SLC3A2
Synthetic peptide: N terminal region of CD98 light chain
Affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.1% sodium azide
P08195
4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE
Rabbit
IgG
50 μg
4°C or -20°C if preferred
Primary
6520
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit