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Cdc42 Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA128295

Catalog No. PIPA128295


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Description

Description

PA1-28295 detects CDC42 from human, mouse, rat samples. PA1-28295 has been successfully used in Western blot applications. The PA1-28295 immunogen is: Full length human CDC42

This protein is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis, and cell progrssion. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrick syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcipt variants.
Specifications

Specifications

Cdc42
Polyclonal
Unconjugated
CDC42
Liquid
CDC42
Full length human CDC42
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P60953, P60766, Q8CFN2
RP1-224A6.5, CDC42Hs, G25K
Chicken
IgY
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
12540, 64465, 998
Documents
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