Cdc42 Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA520764
A suggested positive control is human brain tissue lysate. PA5-20764 can be used with blocking peptide PEP-0878.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.
|A 17 amino acid peptide near the amino terminus of human CDC42.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|P60953, P60766, Q8CFN2|
|RP1-224A6.5, CDC42Hs, G25K; G25K GTP-binding protein; GTP-binding protein, 25kD; cell division control protein 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); growth-regulating protein; small GTP binding protein CDC42|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|12540, 64465, 998|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok