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anti-Cdk7/ p40MO15/CAK Ab-1, Clone: MO-1.1, Thermo Scientific Lab Vision

Mouse Monoclonal Antibody

Specifications

Antigen Cdk7/ p40MO15/CAK Ab-1
Format Purified
Host Species Murine
Immunogen A recombinant 221 amino acid fragment of the C-terminus human p40MO15 protein.
Isotype IgG2b
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Products 9
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS219B
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Epredia
MS219B
200μg/mL 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219B0
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Epredia
MS219B0
200μg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219P
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Epredia
MS219P
200μg/mL 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219B1
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Epredia
MS219B1
200μg/mL 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219P0
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Epredia
MS219P0
200μg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219PCL
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Epredia
MS219PCL
250μg/100μL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219P1ABX
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Epredia
MS219P1ABX
1mg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219PABX
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Epredia
MS219PABX
1mg/mL 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS219P1
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Epredia
MS219P1
200μg/mL 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

CDK7 is cdk activating kinase associated with the 34kDa cyclin H protein, and a 36kDa unnamed protein. CDK7/cyclin H is an integral part of the general transcription factor complex TFIIH; hence is important for activated transcription of polymerase II-dependent promoters and DNA repair. CDK7 is nuclear at all stages of the cell division cycle, except for mitosis indicating that its activity is required for key CDKs operating in distinct cell cycle phases.

Host Species: Mouse
Clone: MO-1.1
Isotype: IgG2b
Cross Reactivity: Human and Rat. Does not react with mouse. Others-not known.
Epitope: 221 amino acid fragment of C-terminus
Immunogen: A recombinant 221 amino acid fragment of the C-terminus human p40MO15 protein.
Molecular Weight: 40kDa
Positive Control: HT29 and LS174T cells
Cellular Localization: Nuclear and cytoplasmic

Ab-1 is well suited for multiple biochemical applications including immunoprecipitation of kinase activity

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Kinase Assay, Western Blotting

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Specifications

Cdk7/ p40MO15/CAK Ab-1
Murine
IgG2b
Purified
A recombinant 221 amino acid fragment of the C-terminus human p40MO15 protein.
Primary
SDS
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