cyclin-dependent kinase inhibitor 1B (p27, Kip1) (B01), Mouse anti-Human, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human CDKN1B protein.
Manufacturer: Abnova Corporation H00001027B01
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeqSequence: MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDGSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATGDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
|cyclin-dependent kinase inhibitor 1B (p27, Kip1)|
|Immunofluorescence, Western Blot|
|Mouse polyclonal antibody raised against a full-length human CDKN1B protein.|
|CDKN1B (AAH01971, 1 a.a. ~ 198 a.a) full-length human protein.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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