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CDw210 Rat anti-Human, PE, Clone: 3F9, BD
Rat Monoclonal Antibody
Supplier: BD Biosciences 556013
Description
Reaacts with 90-110kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNγR (CDw119), IFNα/βR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages. Clone 3F9 is specific for human IL-10R and its binding to the receptor can be blocked by recombinant human IL-10 (rhIL-10). This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Rat
Clone: 3F9
Isotype: IgG2a κ
Species Reactivity: Human
Flow Cytometry
Specifications
CDw210 | |
Monoclonal | |
PE | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human IL-10R alpha Recombinant Protein | |
100 Tests | |
Cell Biology | |
Human | |
IgG2a κ |
Flow Cytometry | |
3F9 | |
IL-10 receptor | |
Rat | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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For Research Use Only.