Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Cellugyrin Mouse, Unlabeled, Clone: 24, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 611128

Catalog No. BDB611128

Add to cart



Neurotransmitter release is mediated by the synaptic vesicle cycle at the presynaptic nerve terminal. This exocytic process involves vesicle docking at the plasma membrane, which is followed by priming and fusion. Following exocytosis, the empty vesicles are recycled for continued neurotransmitter release. Vesicle fusion is mediated by a protein complex consisting of both synaptic vesicle and synaptic plasma membrane components, such as synaptotagmin, synaptobrevin, and synaptogyrin. It is thought that synaptic vesicle-mediated exocytosis is very similar to other exocytic pathways. In line with this idea, cellugyrin is a synaptogyrin-like protein that is widely expressed in non-neuronal tissues. Cellugyrin and synaptogyrin share 47% amino acid sequence identity. Additionally, both cellugyrin and synaptogyrin are phosphorylated in their cytoplasmic tails by pp60c-src. This suggests a role for phosphorylation in the regulation of membrane trafficking. Thus, cellugyrin is a ubiquitously expressed exocytic protein of which synaptogyrin is a specialized neuronal version. However, the exact function of either protein in exocytosis remains to be determined.

Host Species: Mouse
Clone: 24
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Rat Cellugyrin aa. 95-204
Formula Weight [Chemical]: 29kDa

Immunofluorescence, Western Blotting



Affinity Purified
Rat Cellugyrin aa. 95-204
Cell Biology
Murine, Rat
Western Blot
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Store undiluted at -20°C.
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit