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CENPF Rabbit anti-Bovine, Human, Biotin, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522931

Catalog No. PIPA522931


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Description

Description

The kinetophore is a macromolecular structure that is associated with the centromeres of chromosomes and is responsible for establishing and maintaining the connections with the microtubules of the mitotic spindle. The proteins that reside within the chromosomal domain fall into two broad classes: those that associate with the centromere throughout the cell cycle and those that are found at the centromere in a cell cycle specific manner. Members of the first class include CENP-A, CENP-B, and CENP-C. The members of the second class include several ubiquitous cellular proteins such as calmodulin, tubulin, dynein and p34 cdc2 and also CENP-E and CENP-F. CENP-F appears to be the earliest member to interact with the centromere-kinetochore complex. CENP-F also shows a cell-cycle distribution that is both temporally regulated and diverse in terms of the structural components it localizes to and therefore may play a role in several mitotic events. (1-3)
Specifications

Specifications

CENPF
Polyclonal
Biotin
CENPF
Liquid
CENPF
A bacterial fusion protein from the C-terminus of CENP-F.
Affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
1.2 mg/mL
PBS with 0.05% sodium azide
P49454
RP11-262H5.1, CENF, PRO1779, hcp-1, AH antigen, CENP-F kinetochore protein, cell-cycle-dependent 350K nuclear protein, centromere protein F, centromere protein F, 350/400ka (mitosin), kinetochore protein CENPF, mitosin
Rabbit
IgG
50 μL
4° C, store in dark
Primary
1063, 533089
Documents
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