CENPF Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527126
PA5-27126 targets CENPF in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27126 immunogen is synthetic peptide corresponding to a region within amino acids 3148 and 3210 of Human CENPF. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
|Synthetic peptide corresponding to a region within amino acids 3148 and 3210 of Human CENPF|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.01% thimerosal; pH 7|
|CENF, PRO1779, hcp-1, AH antigen, CENP-F kinetochore protein, cell-cycle-dependent 350K nuclear protein, centromere protein F, centromere protein F, 350/400ka (mitosin), kinetochore protein CENPF, mitosin|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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