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CENPF Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527126

Catalog No. PIPA527126


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Description

Description

PA5-27126 targets CENPF in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27126 immunogen is synthetic peptide corresponding to a region within amino acids 3148 and 3210 of Human CENPF. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
Specifications

Specifications

CENPF
Polyclonal
Unconjugated
CENPF
Liquid
CENPF
Synthetic peptide corresponding to a region within amino acids 3148 and 3210 of Human CENPF
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P49454
CENF, PRO1779, hcp-1, AH antigen, CENP-F kinetochore protein, cell-cycle-dependent 350K nuclear protein, centromere protein F, centromere protein F, 350/400ka (mitosin), kinetochore protein CENPF, mitosin
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1063
Documents
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