CENPH Mouse anti-Human, Clone: 1F7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA522523
Peptide Sequence: MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT KQQLLEYKSM VDASEEKTPE QIMQEKQIEA KIEDLENEIE EVKVAFEIKK LALDRMRLST ALKKNLEKIS RQSSVLMDNM KHLLELNKLI MKSQQESWDL EEKLLDIRKK RLQLKQASES KLLEIQTEKN KQKIDLDSME NSERIKIIRQ NLQMEIKITT VIQHVFQNLI LGSKVNWAED PALKEIVLQL EKNVDMMCentromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
|PBS with no preservative; pH 7.4|
|CENP-H, interphase centromere complex protein 35, kinetochore protein CENP-H|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|CENPH (AAH12024, 1 a.a. ∽ 247 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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