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CENPH Mouse anti-Human, Clone: 1F7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA522523

Catalog No. PIMA522523


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Description

Description

Peptide Sequence: MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT KQQLLEYKSM VDASEEKTPE QIMQEKQIEA KIEDLENEIE EVKVAFEIKK LALDRMRLST ALKKNLEKIS RQSSVLMDNM KHLLELNKLI MKSQQESWDL EEKLLDIRKK RLQLKQASES KLLEIQTEKN KQKIDLDSME NSERIKIIRQ NLQMEIKITT VIQHVFQNLI LGSKVNWAED PALKEIVLQL EKNVDMM

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
Specifications

Specifications

CENPH
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9H3R5
CENP-H, interphase centromere complex protein 35, kinetochore protein CENP-H
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
64946
ELISA, Western Blot
1F7
Unconjugated
CENPH
Liquid
CENPH
CENPH (AAH12024, 1 a.a. ∽ 247 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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