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CETP Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1050

Catalog No. PA1050


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Description

Description

PA1-050 detects cholesteryl ester transfer protein (CETP) from human tissues. PA1-050 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~70 kDa band from human liver extracts representing CETP. The PA1-050 immunogen is a synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.This peptide (Cat. No. PEP-209) is available for use in neutralization and control experiments.

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to specifically accelerate the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determit of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. In general, elevated levels of CETP have been associated with increased risk of coronary heart disease.
Specifications

Specifications

CETP
Polyclonal
Unconjugated
CETP
Liquid
CETP
Synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
P11597
Cholesteryl Ester Transfer Protein, Lipid transfer protein I
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1071
Documents
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