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Complement Factor B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526047

Catalog No. PIPA526047


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Description

Description

CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Specifications

Specifications

Complement Factor B
Polyclonal
PBS with 0.09% sodium azide
P00751
AHUS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2, B-factor, properdin, C3 proaccelerator, C3 proactivator, C3/C5 convertase, glycine-rich beta glycoprotein, glycine-rich beta-glycoprotein, properdin factor B
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
629
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CFB
Liquid
CFB
KLH conjugated synthetic peptide between 469-494 amino acids from the central region of human CFB
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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