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CFHR5 Mouse anti-Human, Clone: 390513, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524124

Catalog No. PIMA524124


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Description

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
Specifications

Specifications

CFHR5
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q9BXR6
CFHL5, FHR-5, FHR5, complement factor H-related protein 5, factor H-related protein 5
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
81494
Immunoprecipitation, Western Blot
390513
Unconjugated
CFHR5
Lyophilized
CFHR5
Mouse myeloma cell line NS0-derived recombit human Complement Factor H-related 5/CFHR5 Glu19-Glu569
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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