CFHR5 Mouse anti-Human, Clone: 390513, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524124
Reconstitute at 0.5 mg/mL in sterile PBS.This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
|PBS with 5% trehalose and No Preservative|
|CFHL5, FHR-5, FHR5, complement factor H-related protein 5, factor H-related protein 5|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunoprecipitation, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human Complement Factor H-related 5/CFHR5 Glu19-Glu569|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok