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Chitotriosidase Mouse anti-Human, Clone: 397504, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524132

Catalog No. PIMA524132


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Description

Description

In direct ELISAs, no cross-reactivity with Recombinant human CHI3L1 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Specifications

Specifications

Chitotriosidase
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q13231
CHI3, CHIT, CHITD, chitinase-1, chitotriosidase-1, plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1118
Immunoprecipitation, Neutralization
397504
Unconjugated
CHIT1
Lyophilized
CHIT1
Mouse myeloma cell line NS0-derived recombit human Chitotriosidase/CHIT1 Ala22-Asn466
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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