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CHMP2B Mouse anti-Human, Clone: 2H6-1E6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521591

Catalog No. PIMA521591


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Description

Description

Peptide Sequence: MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Specifications

Specifications

CHMP2B
Monoclonal
0.5 mg/mL
PBS with no preservative; pH 7.4
Q9UQN3
CHMP2.5, DMT1, VPS2-2, VPS2B, VPS2 homolog B, charged multivesicular body protein 2b, chromatin modifying protein 2B, vacuolar protein-sorting-associated protein 2-2
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
25978
ELISA
2H6-1E6
Unconjugated
CHMP2B
Liquid
CHMP2B
CHMP2B (AAH01553.1, 1 a.a. ∽ 213 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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