Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CHMP4B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526536

Catalog No. PIPA526536


Add to cart

Description

Description

This antibody is predicted to react with chicken, mouse, Xenopus and zebrafish based on sequence homology.

CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
Specifications

Specifications

CHMP4B
Polyclonal
PBS with 0.09% sodium azide
Q9H444
C20orf178, CHMP4A, CTPP3, SNF7, SNF7-2, Shax1, VPS32B, Vps32-2, dJ553F4.4, SNF7 homolog associated with Alix 1, Snf7 homologue associated with Alix 1, charged multivesicular body protein 4b, chromatin modifying protein 4B, chromatin-modifying protein 4b, hSnf7-2, hVps32-2, vacuolar protein sorting-associated protein 32-2, vacuolar prote
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
128866
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CHMP4B
Liquid
CHMP4B
KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit