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Cholera Toxin beta Rabbit anti-Bacteria, Biotin, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA173190

Catalog No. PA173190


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Description

Description

The PA1-73190 antibody reacts with Cholera toxin beta subunit. PA1-73190 has been successfully used in ELISA applications. The PA1-73190 antibody was raised against purified Choleragenoid. Store at 4°C for up to 6 months. For long term storage, aliquot and freeze at -20°C. Avoid freeze-thaw cycles.

Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.
Specifications

Specifications

Cholera Toxin beta
Polyclonal
Biotin
Liquid
Rabbit
IgG
1 mL
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Primary
Bacteria
ELISA
4-5 mg/mL
PBS with 0.1% sodium azide; pH 7.2
beta subunit cholera toxin; CTB; VC1456; CTX
Purified Choleragenoid.
Purified
RUO
Antibody
Polyclonal
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