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hCG beta Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA516265

Catalog No. PIPA516265

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PA5-16265 targets Chorionic Gonadotropin Human in IHC (P) applications and shows reactivity with Human samples. The PA5-16265 immunogen is purified Beta-subunit of HCG.

hCG beta is the beta chain of hCG (Human chorionic gonadotropin), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. hCG is made up of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those found on the pituitary hormones FSH, LH ans TSH. However, the beta subunit is different in FSH, LH and TSH and are involved in conferring biological specificity. Maintece of the fetus in the first trimester of pregcy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non-pregt urine and sera but rises sharply during pregcy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and Beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). Diseases associated with Hcg dysfunction include gestational trophoblastic tumor and hydatidiform mole, recurrent 1.
Specifications

Specifications

hCG beta
Polyclonal
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P0DN86
CG-beta, choriogonadotropin subunit beta, chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit
Rabbit
IgG
500 μL
4° C
Primary
1082
Immunohistochemistry (Paraffin)
Unconjugated
CGB3
Liquid
CGB3
Purified Beta-subunit of HCG
Purified
RUO
Antibody
Polyclonal
Human
Documents
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