CHRNA3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524943
This antibody is predicted to react with bovine based on sequence homology.CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
|PBS with 0.09% sodium azide|
|LNCR2, NACHRA3, PAOD2, acetylcholine receptor, nicotinic, alpha 3 (neuronal), cholinergic receptor, nicotinic, alpha polypeptide 3, neuronal acetylcholine receptor subunit alpha-3, neuronal nicotinic acetylcholine receptor, alpha3 subunit|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3|
|Antigen affinity chromatography|
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