Chromogranin A Mouse anti-Human, Clone: 23A1, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific LFMA0140

Catalog No. LFMA0140

Description

A suggested positive control for this product is Bosc23 cells transfected with myc/His-CGA.

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Specifications

• Antigen: Chromogranin A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: P10645
• Gene Symbols: CHGA
• Immunogen: Recombit human CGA protein purified from E.coli
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 23A1
• Gene: CHGA
• Gene Alias: CGA
• Host Species: Mouse
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 1113
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid