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CIC Rabbit anti-Canine, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA146017

Catalog No. PA146017


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Description

Description

PA1-46017 is not recommended for Western blot procedures.

CIC, a human homolog of Drosophila capicua, encodes a high mobility group box transcription factor and is fused to a double homeodomain gene DUX4 as a result of a recurrent chromosomal translocation. It is involved in epidermal growth factor receptor (EGFR) signaling, developmental patterning, and cell fate. In humans, CIC may be involved in granule cell lineage, cerebellar development, and medulloblastoma tumorigenesis. Recent evidence indicates that CIC is involved in Spinocerebellar Ataxia Type 1 (SCA-1) where it interacts directly with the product of the SCA-1 gene Ataxin-1.
Specifications

Specifications

CIC
Polyclonal
Unconjugated
CIC
Liquid
CIC
A synthetic peptide made to a region within residues 1150-1200 of the human Capicua protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunoprecipitation
1 mg/mL
PBS with 0.02% sodium azide
Q96RK0, Q924A2
Capicua , KIAA0306
Rabbit
IgG
100 μg
4° C, do not freeze
Primary
23152, 308435, 484475, 71722
Documents
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