CIRBP Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526146
This antibody is predicted to react with hamster, mouse and rat based on sequence homology.CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3 ft.-untranslated regions (3 ft.-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
|PBS with 0.09% sodium azide|
|CIRP, A18 hnRNP, cold inducible RNA-binding protein, cold-inducible RNA-binding protein, glycine-rich RNA binding protein, glycine-rich RNA-binding protein CIRP|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP|
|Antigen affinity chromatography|
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