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CIRBP Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526146

Catalog No. PIPA526146

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with hamster, mouse and rat based on sequence homology.

CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3 ft.-untranslated regions (3 ft.-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
Specifications

Specifications

CIRBP
Polyclonal
PBS with 0.09% sodium azide
Q14011
CIRP, A18 hnRNP, cold inducible RNA-binding protein, cold-inducible RNA-binding protein, glycine-rich RNA binding protein, glycine-rich RNA-binding protein CIRP
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1153
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CIRBP
Liquid
CIRBP
KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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