Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CLAC-P Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14308

Catalog No. PA14308


Add to cart

Description

Description

PA1-4308 detects CLAC-P (NC3 region) in human and mouse samples. PA1-4308 has been successfully used in Western blotting and immunohistochemistry procedures. By Western blot, this antibody detects a ~70 kDa protein representing CLAC-P (NC3 region) in stable HEK293T cell lines expressing CLAC-P (NC3 region). PA1-4308 does not cross react with COLXIII or COLXXIII proteins. PA1-4308 immunizing peptide corresponds to amino acid residues 430-443 of the NC3 region of human and mouse CLAC-P. Maintain at 4°C for 3 months or at -20°C for longer periods. Avoid freeze/thaw cycles.

Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer ft.s disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD.
Specifications

Specifications

CLAC-P
Polyclonal
Unconjugated
COL25A1
Liquid
COL25A1
Synthetic peptide: D(430) Y N G N L H E A L Q R I T(443) of the NC3 region of human and murine CLAC-P
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9BXS0, Q99MQ5
CLAC, CLACP
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
77018, 84570
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit