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CLASP2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523922

Catalog No. PIPA523922

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with rat based on sequence homology.

CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Specifications

Specifications

CLASP2
Polyclonal
PBS with 0.09% sodium azide
O75122, Q8BRT1
CLIP-associating protein 2, cytoplasmic linker-associated protein 2, multiple asters (Mast)-like homolog 2, protein Orbit homolog 2
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23122, 76499
Flow Cytometry, Western Blot
Unconjugated
CLASP2
Liquid
CLASP2
KLH conjugated synthetic peptide between 998-1026 amino acids from human CLASP2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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